What to expect: Built on the original site of the University of Washington, this hotel became historically famous as the “grandest hotel west of the Mississippi.” Now a Seattle landmark, this bastion of grandeur is listed on the National Register of Historic Places. The hotel welcomes business travelers, tour groups, and vacationers, and is a popular venue for wedding receptions.

In the lobby, gilt-and-crystal chandeliers hang suspended amid pillars, ornate moldings, and hand-burnished oak walls. Asian-style urns and potted greens complement upholstered chairs, black/gold tables, and couches in gold-toned fabrics. An enormous flower arrangement bursts from a stone urn, anchoring the design at center.

Amenity highlights: A state-of-the-art fitness club offers a pool, spa tub, sauna, and weight room; plus treadmills, stationary bikes, stair steppers, and elliptical trainer – all with personal DVD players attached. On the 12th floor, the business center is equipped with computer stations and high-speed Internet access, plus a technology help-desk. Children receive toys and goodies at check-in, while baby amenities range from bottle warmers to night lights. Pets also receive VIP treatment as water dishes, food dishes, and other supplies are kept on hand.

What to expect: The Alexis is set between Pike Place Market and Pioneer Square, three blocks from the waterfront and Seattle Art Museum. Inside the hotel, public areas showcase Northwest art; decor includes antique-style furnishings. The hotel is listed on the National Register of Historic Places.

Amenity highlights: Complimentary services include a morning paper, morning coffee service, an evening wine reception in the lobby, and access to the on-site fitness center and private steam room. The hotel also offers 24-hour room service, valet parking, and the book-filled Library Bistro restaurant, which serves breakfast, lunch, and dinner. And no need to put puppy in the kennel — the Alexis is a pet-friendly hotel.

Insider tip: The artwork display in the hotel lobby and first-floor public area features changing exhibits by top-notch Northwest artists, and is a regular stop on the monthly “First Thursday” art walk, when Pioneer Square-area galleries stay open late, launch new shows, and encourage folks to linger and ponder art while sipping wine and nibbling cheese.